At present there is inadequate information to make recommendations regarding the effectiveness of fish oil in the treatment of active ulcerative colitis.
Ulcerative colitis is an inflammation of the large intestine that causes diarrhea, abdominal pain, rectal bleeding and fever. Because the disease is incurable, the goal of treatment is to cause a reduction in the signs and symptoms painful and annoying. Current options, checked, treatment for ulcerative colitis include corticosteroids, amino salicylates, immunosuppressants and biological agents.
However, these drugs can cause side effects. New treatments are being sought to cause fewer side effects. Fish oil, which is rich in omega-3 fatty acids may reduce inflammation and reduce the need for anti-inflammatory drugs in patients with ulcerative colitis.
Six studies that consider the effects of the oil of fish in active Ulcerative colitis were included in the review. Study quality was mostly poor. A small study showed a positive benefit of treatment in active Ulcerative colitis. However, this result should be interpreted with caution due to the small size of the study and its poor quality.
Due to the limited data, there is insufficient information available to determine if treatment with fish oil is effective for induction of remission in ulcerative colitis.
All about Fish Oil
The fish oil containing omega-3 fatty acids that may be beneficial in reducing inflammation, as observed in the intestine of patients with ulcerative colitis. The effect of daily intake of omega-3 fatty acids for maintenance of remission in ulcerative colitis.
Three studies were included, of whom none reported a reduction in the rate of disease relapse compared to placebo. When studies were pooled for meta-analysis, there was no benefit for omega-3 fatty acids. There were no serious side effects in either study.
None of the studies used enteric coated capsules that allow the release of fish oil in the small intestine. The omega-3 fatty acids (fish oil) without enteric coating seem harmless, but ineffective in maintaining remission in ulcerative colitis. It warrants further studies on enteric coated capsules.