Aspartic acid family of Amino acids

Aspartic acid

Aspartic Acid

The aspartic acid is a non-essential amino acid since it can be synthesized by the human body and therefore negatively charged at neutral pH. Its symbol is D in one letter and Asp code in three letter code. Its chemical formula is C4H7NO4.

It is a neurotransmitter and one of the 20 amino acids with the cells that form proteins. Its biosynthesis takes place by transamination of the oxaloacetic acid, an intermediate metabolite of the Krebs cycle (a metabolic pathway, i.e., a succession of chemical reactions, which form part of the cellular respiration in all aerobic cells).

Carried out in the mitochondria in eukaryotic cells. In prokaryotes, the Krebs cycle is performed in the cytoplasm, specifically in the cytosol. Found mainly in the pituitary gland, the hypothalamus and the testicles.

Like all the amino acids, aspartic acid can be found in two forms called natural isometric (aspartic acid D and L-aspartic acid). D Aspartic acid plays an important role in the production and secretion of hormones, as well as the proper functioning of the nervous system.

Recent research have shown that it acts as a neurotransmitter that is specialized in the parts of the nervous system involved in the production of hormones, also proved to be a stimulator in the release of the hormone luteinizing (LH) and the growth hormone (GH of the pituitary gland).

LH luteinizing hormone, is the chemical Messenger that travels from the pituitary to the testis, where it triggers the production of testosterone. In addition to improving the production of LH, D-aspartic acid has also shown to have a stimulating effect directly in the testes on the production of testosterone.

It is very important to detox the liver and its proper operation and that when combined with other amino acids as molecules able to absorb toxins from the bloodstream.

Functions performed:

These are some of the most important functions performed in the body:

• It helps us improve fatigue and depression.

• It helps to remove ammonia, thus protecting the nervous system.

• Involved in many cellular functions and metabolism in the company of potassium and magnesium , rejuvenating activity.

• It is essential for the maintenance of cardiovascular system , accompanied by magnesium, calcium and potassium.

• Protects the liver aiding the expulsion of ammonia.

• Increases absorption, circulation and use of the following minerals: calcium, magnesium, zinc and potassium through the intestinal mucosa, the blood and cells.

• Help function RNA and DNA , which carry genetic information.

• Plays an important role in the production and secretion of hormones.

• Increases testosterone levels naturally and safely, up to 42%.

• Increased muscle growth.

• Improving the quality of sexual life in men.

• Growth.

• It immunoactivating of the thymus gland.

• Protects against the damaging effects of radiation.

• Specifically involved in the metabolic processes of the Central Nervous System (CNS).

• Participates in the formation of glutamic acid or glutamate.

• Promotes and participates in brain connections and learning.

• It participates in the urea cycle.

• Participates in gluconeogenesis (is an anabolic metabolic pathway that allows the biosynthesis of glucose from non-carbohydrate precursors).

• Stimulates the NMDA (N-methyl-D-aspartate).

• It is involved in the detoxification of the blood.

Its deficiency can cause:

Its deficiency can cause a number of disorders in the body, these are some of them:

• Disorders of the nervous system.

• Tiredness and fatigue.

• Cardiovascular alterations.

• Metabolic alterations.

• Liver disorders by poisoning.

Normal Values:

All measurements are in micromoles per liter (micro mol/L). Normal values ??vary among different laboratories. Talk to your doctor about the meaning of your specific test results.

Children: From 0-26

Adults: From 0-6

Meaning of abnormal values:

An increase in the total level of amino acids in the blood can be due to:

• Eclampsia.
• Fructose intolerance.
• Ketoacidosis (for diabetes).
• Kidney failure.
• Reye syndrome.

A decrease in the total level of amino acids in the blood can be due to:

• Adrenocortical hyperfunction.
• Fever.
• Hartnup’s disease.
• Huntington’s Chorea.
• Malnutrition.
• Nephrotic syndrome.
• Sadfly fever.
• Rheumatoid arthritis.

High or low concentrations of individual plasma amino acids have to be interpreted along with other clinical information. Abnormal results may be due to diet, hereditary problems with the body’s ability to handle the amino acid or drug effects.

Precautions and Facts to consider:

It does not produce side effects, however, people with liver or kidney conditions, pregnant women, epilepsy, ischemic brain injury and Alzheimer’s disease, should not ingest large amounts of amino acids without the recommendations of a medical professional.

Recommended Dose

• You can make a loading phase of 8-10 days, which would consume 2 doses of 3 grams to throughout the day, to continue with a single shot, or take a dose of 3 grams from the beginning.

• It should be used for a period of 4 to 8 weeks, resting at least 1 month, before starting a new take.

• It is preferable to ingest without food and other supplements, especially other amino acids.

• With high-fat diets have higher levels of testosterone.

• Combined with the amino acid Sarcosine, also it seems to give better results.

Aspartic acid-rich foods:

Here are some of them:

Animal origin:

• Carnes.
• Chicken.
• Fish.
• Eggs.
• Dairy.

Plant origin:

• Legumes.
• Sugarcane.
• Molasses.
• Nuts: Walnuts, pistachios, chestnuts, almonds.
• Grains: Oats, Corn .
• Seeds: Sesame, sunflower seeds, pine nuts.
• Vegetables and Fruits: apricot, plums, oranges, pears, papaya, bananas, grapes, mangoes, figs, apples, currants.

Diseases in which its use can be recommended:

These are some of the diseases where the aspartic acid, may be preferred:

• Tiredness.
• Chronic Fatigue.
• Diseases in which the use of calcium , magnesium , potassium and zinc , becomes necessary.
• Liver: hepatic ammonia poisoning. Hepatic congestion.
• Disorders of the Nervous System: Depression. Anxiety. Anguish. stress. Insomnia.
• Eating disorders.
• Disorders cardiovascular, such as arteriosclerosis or lack of elasticity and resistance in the blood vessels.
• Indirectly, could help in the prevention of osteoporosis.
• By increasing potassium absorption, could help the problems of fluid retention.
• By increasing the absorption of zinc, may help the health of the hair and nails.
• Disorders of growth.
• Disorders of the male sexual functions. Impotence.
• Athletes who require an increase in muscle, power and energy.
• Radiation.
• Disorders of learning.

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